Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635406 | 0.80 | NR4A1 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7996247 | 0.80 | CA1 (0.42) | CA1CA2CA4CA7CYP1A2 | |
| SCHEMBL21674126 | 0.80 | ALDH1A1 (0.43) | CA1CA2CA4CA7CYP1A2 | |
| SCHEMBL7978583 | 0.77 | MAPT (0.42) | CA1CA2CA4CA7CYP1A2 | |
| SCHEMBL42391 | 0.72 | ERN1 (0.42) | ALDH1A1KDM4ELMNAAMY1APKM | |
| SCHEMBL27563320 | 0.72 | AMY1A (0.38) | ALDH1A1KDM4EAMY1APKMMAPT | |
| SCHEMBL16958007 | 0.72 | NFE2L2 (0.41) | ALDH1A1LMNAL3MBTL1AMY1APKM | |
| SCHEMBL21674219 | 0.72 | CYP2C9 (0.36) | CA1CA2CA4CA7CYP1A2 | |
| SCHEMBL7245153 | 0.71 | KDM4E (0.67) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| Urea SCHEMBL28877160 | 0.70 | ERN1 (0.43) | ALDH1A1KDM4EPKMRELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010880-A1 | NEW CRTH2 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2013-01-24 | — | — | WO | disclosed |