Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETDB1 | Q15047 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537180 | 0.81 | MTNR1A (0.43) | SETDB1MTNR1AMTNR1BHDAC1HDAC6 | |
| SCHEMBL13104293 | 0.79 | SETDB1 (0.56) | SETDB1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL6248360 | 0.79 | NPC1 (0.60) | SETDB1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL31705342 | 0.79 | KDM4A (0.44) | NPC1RAB9AALDH1A1HDAC6FFAR4 | |
| SCHEMBL3147876 | 0.78 | CYP1A2 (0.42) | SETDB1HDAC1HDAC6NPSR1RIPK1 | |
| SCHEMBL102342 | 0.77 | RIPK1 (0.61) | SETDB1NPC1RAB9AMTNR1AALDH1A1 | |
| SCHEMBL27810759 | 0.75 | SETDB1 (0.51) | SETDB1NPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL28688067 | 0.74 | FFAR4 (0.46) | ALDH1A1KDM4ENPSR1FFAR4KMT2A | |
| SCHEMBL8228622 | 0.73 | PDE10A (0.52) | SETDB1NPC1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL14224747 | 0.73 | SRC (0.59) | SETDB1NPC1RAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334711-B1 | DERIVATIVES OF PYRROLE, DIAZOLE, TRIAZOLE OR TETRAZOLE FOR COMBATING ARTHROPODS | BAYER CROPSCIENCE AG (DE) | 2020-09-23 | — | — | EP | disclosed |
| WO-2013010880-A1 | NEW CRTH2 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2013-01-24 | — | — | WO | disclosed |