SCHEMBL1463611

SCHEMBL1463611

C=C(C)C(=O)OC(C)OC(=O)/C=C\C(=O)OC(C)OC(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.42
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.39
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
THRB P10828 1/20 0.31
CA12 O43570 1/20 0.30
AKR1B10 O60218 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
AKR1B1 P15121 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155941 1.00 HCAR2 (0.42) HCAR2TSHRALDH1A1KEAP1NFE2L2
SCHEMBL9162974 1.00 HCAR2 (0.42) HCAR2TSHRALDH1A1KEAP1NFE2L2
SCHEMBL1463616 0.93 HCAR2 (0.55) HCAR2TSHRALDH1A1
SCHEMBL6898244 0.93 HCAR2 (0.55) HCAR2TSHRALDH1A1
SCHEMBL10613464 0.90 TSHR (0.37) HCAR2TSHRALDH1A1
SCHEMBL10613451 0.90 TSHR (0.37) HCAR2TSHRALDH1A1
SCHEMBL538063 0.87 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL713871 0.86 TSHR (0.39) TSHRALDH1A1
SCHEMBL6904341 0.84 TSHR (0.48) TSHRALDH1A1THRB
Ethylene SCHEMBL4150916 0.84 TSHR (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP claimed
CN-120192680-A Aluminum pigment applied to UV coating and preparation method thereof 合肥旭阳铝颜料有限公司 2025-06-24 CN claimed
US-12337043-B2 Curable radiopaque substance MERZ DENTAL GMBH (DE) 2025-06-24 US claimed
US-20240225962-A9 CURABLE RADIOPAQUE SUBSTANCE MERZ DENTAL GMBH (DE) 2024-07-11 US claimed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
CN-118006237-A Folding screen protective film and preparation method thereof 深圳市精恒光电科技有限公司 2024-05-10 CN claimed
US-20240130933-A1 CURABLE RADIOPAQUE SUBSTANCE MERZ DENTAL GMBH (DE) 2024-04-25 US claimed
US-11857649-B2 Curable radiopaque substance MERZ DENTAL GMBH (DE) 2024-01-02 US claimed
CN-117050601-A Fluorine electronic protective coating and preparation method thereof 广东聚微新材料科技有限公司 2023-11-14 CN claimed
CN-115463037-B Dental pretreatment agent composition and preparation method thereof 辽宁爱尔创生物材料有限公司 2023-09-22 CN claimed
EP-1133971-B1 Cationically polymerizable adhesive composition UNIV MISSOURI (US) 2005-11-30 EP claimed
EP-1272581-B1 CURABLE POLYMERIC COMPOSITIONS SARTOMER CO INC (US) 2004-04-28 EP claimed
US-6610759-B1 Bonding to hard tissue CURATORS OF THE UNIVERSITY OF MISSOURI 2003-08-26 US claimed
EP-1133971-A1 Cationically polymerizable adhesive composition THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2001-09-19 EP claimed
EP-1126792-A1 ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE Nathoo, Salim A. (US) 2001-08-29 EP claimed
WO-2000025697-A1 ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE NATHOO SALIM A (US) 2000-05-11 WO claimed
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP claimed
US-4913939-A Reaction product of cyclic anhydride and hydroxy compound; adhesion of adhesives REM SYSTEMS, INC. (US) 1990-04-03 US claimed
US-4863993-A Surface priming composition for proteinaceous substrates; method of making and using same OPI PRODUCTS, INC. (US) 1989-09-05 US claimed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 HCAR2 529/4885TSHR 4596/4885ALDH1A1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.