SCHEMBL1463616

SCHEMBL1463616

C=C(C)C(=O)OC(C)OC(=O)C=CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.55
TSHR P16473 3/20 0.36
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GAA P10253 1/20 0.33
TP53 P04637 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
EGLN3 Q9H6Z9 1/20 0.32
ALOX15 P16050 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31
GABRA1 P14867 2/20 0.31
GABRB1 P18505 2/20 0.31
GABRG2 P18507 2/20 0.31
GABRB3 P28472 2/20 0.31
GABRA5 P31644 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898244 1.00 HCAR2 (0.55) HCAR2TSHRALDH1A1KDM4EMAPT
SCHEMBL1463611 0.93 HCAR2 (0.42) HCAR2TSHRALDH1A1
SCHEMBL9155941 0.93 HCAR2 (0.42) HCAR2TSHRALDH1A1
SCHEMBL9162974 0.93 HCAR2 (0.42) HCAR2TSHRALDH1A1
SCHEMBL10613464 0.84 TSHR (0.37) HCAR2TSHRALDH1A1
SCHEMBL10613451 0.84 TSHR (0.37) HCAR2TSHRALDH1A1
SCHEMBL28908593 0.81 HCAR2 (0.63) HCAR2TSHRALDH1A1KDM4EMAPT
Fumaric Acid SCHEMBL7512233 0.81 HCAR2 (0.57) HCAR2TSHRALDH1A1KDM4EMAPT
SCHEMBL538063 0.80 TSHR (0.50) TSHRALDH1A1TDP1HSD17B10
SCHEMBL19205434 0.79 HCAR2 (0.61) HCAR2TSHRALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122008641-A Packaging film, preparation method and packaging bag 湖南大道新材料有限公司 2026-05-12 CN claimed
EP-3782599-B1 DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2025-09-17 EP claimed
US-12337043-B2 Curable radiopaque substance MERZ DENTAL GMBH (DE) 2025-06-24 US claimed
CN-120192680-A Aluminum pigment applied to UV coating and preparation method thereof 合肥旭阳铝颜料有限公司 2025-06-24 CN claimed
CN-117025052-B Water-based superhydrophobic consolidation material for TIT (tungsten inert gas) embedding seal layer 北京中科安途交通科技有限公司 2025-05-06 CN claimed
CN-119074565-A Water-based glass ion water heater and obtained tooth restoration material 深圳爱尔创口腔技术有限公司 2024-12-06 CN claimed
CN-118562416-A Silicon-based negative electrode binder of high-performance lithium ion battery and preparation method thereof 东营市海科瑞林化工有限公司 2024-08-30 CN claimed
US-20240225962-A9 CURABLE RADIOPAQUE SUBSTANCE MERZ DENTAL GMBH (DE) 2024-07-11 US claimed
CN-118146745-A High-temperature-resistant adhesive, preparation method thereof and high-temperature-resistant adhesive tape 苏州高泰电子技术股份有限公司 2024-06-07 CN claimed
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
US-6610759-B1 Bonding to hard tissue CURATORS OF THE UNIVERSITY OF MISSOURI 2003-08-26 US claimed
EP-1133971-A1 Cationically polymerizable adhesive composition THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2001-09-19 EP claimed
EP-1126792-A1 ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE Nathoo, Salim A. (US) 2001-08-29 EP claimed
WO-2000025697-A1 ANTIMICROBIAL COMPOSITIONS THAT PROTECT SKIN AND DENTAL TISSUE NATHOO SALIM A (US) 2000-05-11 WO claimed
EP-0325038-B1 Surface priming composition for proteinaceous substrates, method of making and using same OPI PROD INC (US) 1993-11-03 EP claimed
US-5089051-A Photopolymerizable (meth)acryloyloxyalkyl hydrogen phosphates and mono- and dicarboxylic acid (meth)acryloyloxyethyl esters; high bonding strength HERAEUS KULZER GMBH (DE) 1992-02-18 US claimed
US-4913939-A Reaction product of cyclic anhydride and hydroxy compound; adhesion of adhesives REM SYSTEMS, INC. (US) 1990-04-03 US claimed
US-4863993-A Surface priming composition for proteinaceous substrates; method of making and using same OPI PRODUCTS, INC. (US) 1989-09-05 US claimed
EP-0325038-A2 Surface priming composition for proteinaceous substrates, method of making and using same OPI PRODUCTS, INC. (US) 1989-07-26 EP claimed
US-4275142-A CONJUGATED DIOLEFIN-ACRYLIC ACID OR ANHYDRIDE COPOLYMER, PHOTOSENSITIZER JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 HCAR2 529/4885TSHR 4596/4885ALDH1A1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.