Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.78 |
| ▸ | CA1 | P00915 | 4/20 | 0.78 |
| ▸ | CA2 | P00918 | 4/20 | 0.78 |
| ▸ | CA9 | Q16790 | 4/20 | 0.78 |
| ▸ | CLTC | Q00610 | 9/20 | 0.65 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | NGFR | P08138 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856490 | 0.89 | CA12 (0.76) | CA12CA1CA2CA9CLTC | |
| SCHEMBL2280844 | 0.86 | CA12 (0.71) | CA12CA1CA2CA9CLTC | |
| SCHEMBL2280848 | 0.86 | CA12 (0.71) | CA12CA1CA2CA9CLTC | |
| SCHEMBL3853199 | 0.85 | CA12 (0.70) | CA12CA1CA2CA9CLTC | |
| SCHEMBL14636204 | 0.84 | CLTC (0.72) | CA12CA1CA2CA9CLTC | |
| SCHEMBL2285573 | 0.81 | FTO (0.72) | CA12CA1CA2CA9CLTC | |
| SCHEMBL14636506 | 0.81 | CLTC (0.67) | CA12CA1CA2CA9CLTC | |
| SCHEMBL29483205 | 0.78 | CLTC (0.98) | CA12CA1CA2CA9CLTC | |
| SCHEMBL1893251 | 0.78 | FTO (0.72) | CA12CA1CA2CA9CLTC | |
| SCHEMBL1901643 | 0.78 | FTO (0.72) | CA12CA1CA2CA9CLTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A9 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |