Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLTC | Q00610 | 13/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14636204 | 0.88 | CLTC (0.72) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL14636024 | 0.83 | CLTC (0.79) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL14635858 | 0.81 | KDM4E (0.69) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL14636119 | 0.81 | CA12 (0.78) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL27169540 | 0.80 | NPSR1 (0.73) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL29483205 | 0.80 | CLTC (0.98) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL13893856 | 0.78 | CYP1B1 (0.71) | CLTCNPSR1KDM4EHDAC3HDAC4 | |
| SCHEMBL2365090 | 0.77 | MPO (0.58) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL2365089 | 0.77 | MPO (0.58) | CLTCNPSR1CA12CA1CA2 | |
| SCHEMBL14636004 | 0.77 | CLTC (0.79) | CLTCNPSR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010218-A1 | INHIBITION OF CLATHRIN | FREIE UNIVERSITÄT BERLIN (DE) | 2013-01-24 | — | — | WO | disclosed |