Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652444 | 0.95 | KDM4E (0.43) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15417299 | 0.94 | POLB (0.41) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15250841 | 0.89 | CA12 (0.43) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15203372 | 0.84 | POLB (0.39) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15594582 | 0.84 | ALDH1A1 (0.53) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15249162 | 0.81 | CA12 (0.43) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL18597673 | 0.80 | GAA (0.37) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL20819758 | 0.80 | TSHR (0.41) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL1415213 | 0.78 | GPR35 (0.57) | POLBTSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL15028923 | 0.78 | JAK2 (0.56) | TSHRHSD17B10ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165266-A1 | RING CLOSURE REACTION | FLEXENABLE LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
| US-20200165266-A1 | RING CLOSURE REACTION | FLEXENABLE LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
| CN-111194313-A | Ring closure reaction | 弗莱克因艾伯勒有限公司 | 2020-05-22 | — | — | CN | disclosed |
| WO-2019011826-A1 | RING CLOSURE REACTION | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |
| WO-2019011826-A1 | RING CLOSURE REACTION | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |
| US-9761805-B2 | Organic semiconductors | MERCK PATENT GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| US-9761805-B2 | Organic semiconductors | MERCK PATENT GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| US-9761805-B2 | Organic semiconductors | MERCK PATENT GMBH (DE) | 2017-09-12 | — | — | US | disclosed |
| EP-2734528-B1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| EP-2734528-B1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2017-03-29 | — | — | EP | disclosed |
| US-9096716-B2 | Chemicals and the synthesizing methods thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2015-08-04 | — | — | US | disclosed |
| US-20140163191-A1 | CHEMICALS AND THE SYNTHESIZING METHODS THEREOF | NATION CHIAO TUNG UNIVERSITY (TW) | 2014-06-12 | — | — | US | disclosed |
| US-20140158949-A1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140158949-A1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140158949-A1 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| EP-2734528-A2 | ORGANIC SEMICONDUCTORS | Merck Patent GmbH (DE) | 2014-05-28 | — | — | EP | disclosed |
| CN-103649096-A | Organic semiconductors | MERCK PATENT GMBH | 2014-03-19 | — | — | CN | disclosed |
| US-8623993-B2 | Chemicals and the synthesizing methods thereof | NATIONAL CHAIO TUNG UNIVERSITY (TW) | 2014-01-07 | — | — | US | disclosed |
| WO-2013010614-A2 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013010614-A2 | ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165266-A1 | RING CLOSURE REACTION | LIG4, ATG7, RNF4 | POLB 640/4885TSHR 4369/4885HSD17B10 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.