Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506352 | 0.87 | THRB (0.42) | LPAR2LPAR3LPAR1MEN1KMT2A | |
| SCHEMBL29236401 | 0.87 | THRB (0.42) | LPAR2LPAR3LPAR1MEN1KMT2A | |
| SCHEMBL7754449 | 0.85 | THRB (0.37) | LPAR2LPAR3LPAR1MEN1KMT2A | |
| SCHEMBL7170235 | 0.83 | LPAR2 (0.52) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL7170228 | 0.83 | LPAR2 (0.52) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL5701264 | 0.82 | LPAR2 (0.50) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL489663 | 0.82 | LPAR2 (0.50) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL5701269 | 0.82 | LPAR2 (0.50) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL5701279 | 0.82 | LPAR2 (0.50) | LPAR2LPAR3LPAR1FAAHTRPV1 | |
| SCHEMBL5701277 | 0.82 | LPAR2 (0.50) | LPAR2LPAR3LPAR1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010747-A1 | PROCESS FOR REDUCING CARBOXYLIC ESTERS OR CARBOXYLIC LACTONES TO THE CORRESPONDING ETHERS | EVONIK GOLDSCHMIDT GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |