Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15497996 | 0.86 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL13465715 | 0.86 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL713231 | 0.86 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL6632346 | 0.76 | NOD1 (0.40) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL627305 | 0.76 | TGFBR1 (0.39) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL627304 | 0.76 | TGFBR1 (0.39) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL5562691 | 0.76 | ACE (0.43) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10602859 | 0.76 | FOLH1 (0.42) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL8241166 | 0.75 | FOLH1 (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL14470445 | 0.75 | FOLH1 (0.38) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945940-B2 | Mass- and property-tuned variable mass labeling reagents and analytical methods for simultaneous peptide sequencing and multiplexed protein quantification using thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2015-02-03 | — | — | US | disclosed |
| EP-2382184-A2 | MASS- AND PROPERTY-TUNED VARIABLE MASS LABELING REAGENTS AND ANALYTICAL METHODS FOR SIMULTANEOUS PEPTIDE SEQUENCING AND MULTIPLEXED PROTEIN QUANTIFICATION USING THEREOF | Postech Academy-industry Foundation (KR) | 2011-11-02 | — | — | EP | disclosed |
| US-20110071040-A1 | MASS- AND PROPERTY-TUNED VARIABLE MASS LABELING REAGENTS AND ANALYTICAL METHODS FOR SIMULTANEOUS PEPTIDE SEQUENCING AND MULTIPLEXED PROTEIN QUANTIFICATION USING THEREOF | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2011-03-24 | — | — | US | disclosed |
| WO-2010008159-A2 | MASS- AND PROPERTY-TUNED VARIABLE MASS LABELING REAGENTS AND ANALYTICAL METHODS FOR SIMULTANEOUS PEPTIDE SEQUENCING AND MULTIPLEXED PROTEIN QUANTIFICATION USING THEREOF | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071040-A1 | MASS- AND PROPERTY-TUNED VARIABLE MASS LABELING REAGENTS AND ANALYTICAL METHODS FOR SIMULTANEOUS PEPTIDE SEQUENCING AND MULTIPLEXED PROTEIN QUANTIFICATION USING THEREOF | SRMS, PTMS, QPCTL | MAPT 3118/4885KDM4E 1440/4885THRB 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.