Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CDC7 | O00311 | 3/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635631 | 0.89 | TRPM8 (0.50) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL14636748 | 0.86 | CYP3A4 (0.55) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL14637387 | 0.85 | MEN1 (0.47) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL290490 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL14654129 | 0.83 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL14654292 | 0.83 | NPC1 (0.54) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL15991054 | 0.83 | NPC1 (0.54) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL10974241 | 0.82 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL11390772 | 0.82 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL14652371 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-10-02 | — | — | US | disclosed |
| EP-2731427-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013010946-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013010946-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296064-A1 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | PTMS, THOP1, TH | CYP1A2 329/4885CYP3A4 778/4885CYP2C19 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.