SCHEMBL290490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14636748	0.88	CYP3A4 (0.55)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL4497703	0.86	SMN1; SMN2 (0.59)	CYP2C19LMNAMEN1KMT2AMAPT
	SCHEMBL14636639	0.85	CYP1A2 (0.52)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL14654129	0.85	CYP1A2 (0.71)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL290342	0.82	CDC7 (0.72)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL14141917	0.82	CYP1A2 (0.57)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL14635631	0.81	TRPM8 (0.50)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL15991054	0.80	NPC1 (0.54)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL14654292	0.80	NPC1 (0.54)	CYP1A2CYP3A4CYP2C19LMNAMEN1
	SCHEMBL14637387	0.80	MEN1 (0.47)	CYP1A2CYP3A4CYP2C19LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.