Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31390069 | 0.79 | HTR2A (0.34) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL21503406 | 0.79 | PRMT6 (0.34) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL21503651 | 0.79 | PRMT6 (0.34) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| Hydrochloric Acid SCHEMBL21492708 | 0.78 | PRMT6 (0.33) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| Hydrochloric Acid SCHEMBL21492706 | 0.78 | PRMT6 (0.33) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL950746 | 0.77 | EIF2AK4 (0.40) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL21503314 | 0.75 | MPO (0.43) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL28858399 | 0.74 | IDH1 (0.35) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL26744414 | 0.74 | FAAH (0.45) | HTR2AHTR2CHTR2BIDH1EIF2AK4 | |
| SCHEMBL743741 | 0.74 | IDH1 (0.35) | HTR2AHTR2CHTR2BIDH1EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |