SCHEMBL14637149

SCHEMBL14637149

C1CCC2=NCCCN2CC1.CC(=O)N(C)C

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
INMT O95050 5/20 0.70
USP2 O75604 1/20 0.70
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
PTGS2 P35354 1/20 0.32
POLB P06746 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
GFER P55789 1/20 0.32
SLC29A1 Q99808 1/20 0.31
MAPK1 P28482 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14636132 0.93 INMT (0.65) INMTUSP2SMN1; SMN2
Acetic Acid SCHEMBL1691547 0.90 INMT (0.75) INMTUSP2SMN1; SMN2ALDH1A1LMNA
Acetic Acid SCHEMBL1691544 0.90 INMT (0.75) INMTUSP2SMN1; SMN2ALDH1A1LMNA
Acetic Acid SCHEMBL1691556 0.90 INMT (0.75) INMTUSP2SMN1; SMN2ALDH1A1LMNA
Bicarbonate SCHEMBL6363121 0.88 INMT (0.84) INMTUSP2SMN1; SMN2CYP1A2CYP2C19
Bicarbonate SCHEMBL6183133 0.86 INMT (0.83) INMTUSP2CYP1A2CYP2C19MAPK1
Bicarbonate SCHEMBL6184428 0.86 INMT (0.81) INMTUSP2SMN1; SMN2CYP1A2CYP2C19
Methyl Alcohol SCHEMBL3239319 0.86 INMT (0.88) INMTUSP2SMN1; SMN2ACHE
SCHEMBL22344825 0.84 INMT (0.66) INMTUSP2SMN1; SMN2ALDH1A1LMNA
SCHEMBL2401189 0.84 INMT (1.00) INMTUSP2SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2734499-A1 MEROCYANINE DERIVATIVES BASF SE (DE) 2014-05-28 EP disclosed
WO-2013011480-A1 MEROCYANINE DERIVATIVES BASF SE (DE) 2013-01-24 WO disclosed