Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 5/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1691556 | 1.00 | INMT (0.75) | INMTUSP2SMN1; SMN2GFERGAA | |
| Acetic Acid SCHEMBL1691544 | 1.00 | INMT (0.75) | INMTUSP2SMN1; SMN2GFERGAA | |
| Bicarbonate SCHEMBL6363121 | 0.94 | INMT (0.84) | INMTUSP2SMN1; SMN2CYP1A2CYP2C19 | |
| Bicarbonate SCHEMBL6184428 | 0.93 | INMT (0.81) | INMTUSP2SMN1; SMN2CYP1A2CYP2C19 | |
| Acetic Acid SCHEMBL2694265 | 0.93 | INMT (0.74) | INMTUSP2SMN1; SMN2GFERGAA | |
| Bicarbonate SCHEMBL6183133 | 0.93 | INMT (0.83) | INMTUSP2CYP1A2CYP2C19 | |
| Acetic Acid SCHEMBL23577659 | 0.91 | INMT (0.72) | INMTUSP2SMN1; SMN2GFERGAA | |
| SCHEMBL14637149 | 0.90 | INMT (0.70) | INMTUSP2SMN1; SMN2GFERPOLB | |
| Propionic Acid SCHEMBL17359876 | 0.90 | INMT (0.70) | INMTUSP2GAARAB9AALDH1A1 | |
| Methyl Alcohol SCHEMBL3239319 | 0.89 | INMT (0.88) | INMTUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010334-A1 | IONIC LIQUIDS FOR SOLUBILIZING POLYMERS | BASF SE (DE) | 2012-01-12 | — | — | US | disclosed |
| US-20100048829-A1 | IONIC LIQUIDS FOR SOLUBILIZING POLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048829-A1 | IONIC LIQUIDS FOR SOLUBILIZING POLYMERS | ADM2, COIL, CEL | INMT 163/4885USP2 3706/4885SMN1; SMN2 1922/4885 |
| US-20120010334-A1 | IONIC LIQUIDS FOR SOLUBILIZING POLYMERS | ADM2, COIL, CEL | INMT 163/4885USP2 3706/4885SMN1; SMN2 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.