Methyl Alcohol

Methyl Alcohol

SCHEMBL3239319

C1CCC2=NCCCN2CC1.CO

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INMT O95050 4/20 0.88
USP2 O75604 2/20 0.88
ACHE P22303 4/20 0.35
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NOS3 P29474 2/20 0.32
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16583523 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL2401189 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL17417853 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL6853620 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL2734323 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL10601682 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
SCHEMBL3047 0.94 INMT (1.00) INMTUSP2ACHESMN1; SMN2TDP1
Iodide SCHEMBL23365018 0.91 INMT (0.95) INMTUSP2ACHESMN1; SMN2TDP1
Bromide SCHEMBL8469764 0.91 INMT (0.95) INMTUSP2ACHESMN1; SMN2TDP1
Ammonia Solution, Strong SCHEMBL6834929 0.91 INMT (0.95) INMTUSP2ACHESMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344048-B2 Epoxy resin-forming liquid preparation containing inorganic particle NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-01-01 US disclosed
US-20100137475-A1 EPOXY RESIN-FORMING LIQUID PREPARATION CONTAINING INORGANIC PARTICLE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-03 US disclosed
EP-2166037-A1 EPOXY RESIN-FORMING LIQUID PREPARATION CONTAINING INORGANIC PARTICLE Nissan Chemical Industries, Ltd. (JP) 2010-03-24 EP disclosed
EP-1045833-B1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER (US) 2005-11-02 EP disclosed
US-20050101653-A1 Combination therapy for the treatment of migraine SANDS GEORGE H (US) 2005-05-12 US disclosed
US-6608070-B1 Useful for treatment of medical condition in which prostaglandins are implicated as pathogens NAKAO KAZUNARI (JP) 2003-08-19 US disclosed
US-6555540-B1 Treatment of diabetic complications such as neuropathy, nephropathy, retinopathy and cardiomyopathy; for example zopolrestat and rofecoxib PFIZER INC 2003-04-29 US disclosed
US-6476042-B1 Combination therapy for the treatment of migraine PFIZER INC. 2002-11-05 US disclosed
EP-1064965-A2 Combinations of aldose reductase inhibitors and selective cyclooxygenase-2 inhibitors Pfizer Products Inc. (US) 2001-01-03 EP disclosed
EP-1064966-A2 Combination of an 5HT1 receptor antagonist, caffeine and a cyclooxygenase-2 inhibitor for the treatment of migraine Pfizer Products Inc. (US) 2001-01-03 EP disclosed
EP-1051995-A2 5HT1 receptor agonists and a cox-2 inhibitor or NSAID for the treatment of migraine Pfizer Products Inc. (US) 2000-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101653-A1 Combination therapy for the treatment of migraine HTR1A, HTR2A, HTR1B INMT 645/4885USP2 2393/4885ACHE 614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.