Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183112 | 0.87 | MME (0.50) | ALDH1A1MME | |
| SCHEMBL14637806 | 0.81 | ALOX5 (0.43) | MMP9MMP8MMP13LMNAALDH1A1 | |
| SCHEMBL11862111 | 0.81 | SOAT1 (0.46) | ALDH1A1MME | |
| SCHEMBL11862095 | 0.81 | SOAT1 (0.46) | ALDH1A1MME | |
| SCHEMBL11593762 | 0.79 | KDM4E (0.49) | LMNAALDH1A1PPARGPPARA | |
| SCHEMBL11042231 | 0.79 | HMGCR (0.44) | ALDH1A1MME | |
| SCHEMBL7077499 | 0.78 | MME (0.56) | ALDH1A1MME | |
| SCHEMBL28896749 | 0.77 | CTRC (0.58) | LMNA | |
| SCHEMBL3631075 | 0.76 | MME (0.52) | MME | |
| SCHEMBL18248605 | 0.74 | ALDH1A1 (0.42) | MMP9MMP8MMP13LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2732033-A1 | LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME | Novozymes A/S (DK) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013010783-A1 | LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2013-01-24 | — | — | WO | disclosed |