SCHEMBL146378

SCHEMBL146378

Cc1ccc2c([nH]c3ccccc32)c1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.66
MAPT P10636 3/20 0.58
MAPK1 P28482 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
GABRP O00591 2/20 0.53
GABRD O14764 2/20 0.53
GABRA1 P14867 2/20 0.53
GABRB1 P18505 2/20 0.53
GABRG2 P18507 2/20 0.53
GABRB3 P28472 2/20 0.53
GABRA5 P31644 2/20 0.53
GABRA3 P34903 2/20 0.53
GABRA2 P47869 2/20 0.53
GABRB2 P47870 2/20 0.53
GABRA4 P48169 2/20 0.53
GABRE P78334 2/20 0.53
GABRA6 Q16445 2/20 0.53
GABRG1 Q8N1C3 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29726990 1.00 KIF11 (0.66) KIF11MAPTMAPK1NPSR1MEN1
Hydrochloric Acid SCHEMBL572039 0.98 KIF11 (0.63) KIF11MAPTMAPK1NPSR1MEN1
Ammonia Solution, Strong SCHEMBL28022012 0.98 KIF11 (0.63) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL29370563 0.85 STING1 (0.60) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL30022665 0.85 STING1 (0.60) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL8643080 0.85 STING1 (0.60) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL20348818 0.82 KIF11 (0.46) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL26373210 0.82 KIF11 (0.62) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL23166719 0.81 KIF11 (0.56) KIF11MAPTMAPK1NPSR1MEN1
SCHEMBL8802530 0.81 KIF11 (0.56) KIF11MAPTMAPK1NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117649895-A Method and system for predicting ground color layer effect of dimethyl carbazolyl molecules in sandstone transmission layer 中国石油大学(北京) 2024-03-05 CN claimed
CN-115561350-A Method for comprehensively tracing oil gas migration based on nitrogen, sulfur and oxygen compounds 重庆科技学院 2023-01-03 CN claimed
CN-109627215-A A kind of fluorescent material, the preparation method of fluorescent material, display panel and display device 京东方科技集团股份有限公司 2019-04-16 CN claimed
CN-107074804-A Carbazole derivates 百时美施贵宝公司 2017-08-18 CN claimed
CN-104179494-B A kind of method of Indication of Oil-Gas migration agent and Migration mark 中国石油大学(华东) 2017-06-27 CN claimed
CN-104165936-B The detection method of nitrogen-containing compound in a kind of rock extracts CHINA UNIVERSITY OF GEOSCIENCES (WUHAN) (CN) 2016-03-16 CN claimed
CN-104179494-A Method for indicating petroleum migration power and modes UNIV CHINA PETROLEUM 2014-12-03 CN claimed
CN-104165936-A Detection method of nitrogen-containing compound from rock extract UNIV CHINA GEOSCIENCES WUHAN 2014-11-26 CN claimed
CN-101603957-B Gas phase chromatography-flying time mass spectrum analysis method of carbazole compounds RES INST OF EXPLORATION & DEV DAQING OILFIELD CO LTD 2011-11-02 CN claimed
CN-101603957-A A kind of gas phase chromatography-flying time mass spectrum analysis method of carbazole compound RES INST OF EXPLORATION & DEV (CN) 2009-12-16 CN claimed
JP-3251564-A None JP disclosed
CN-122080034-A Polycyclic aromatic compound and organic electroluminescent element 2026-05-26 CN disclosed
CN-122059973-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2026-05-19 CN disclosed
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
EP-4635960-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-10-22 EP disclosed
US-20060252837-A1 Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-11-09 US disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
US-20040115476-A1 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound MERCK PATENT GMBH (DE) 2004-06-17 US disclosed
EP-1424381-A2 Organic electroluminescent element, and display and illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2004-06-02 EP disclosed
JP-H03251564-A DIMETHYLCARBAZOLE DERIVATIVE TAISHO PHARMACEUT CO LTD 1991-11-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252837-A1 Cyclic diamine derivatives useful as agents for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism; inhibit activated blood coagulation factor X F2, C1S, C9 KIF11 3969/4885MAPT 4451/4885MAPK1 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.