Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29726990 | 0.98 | KIF11 (0.66) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL146378 | 0.98 | KIF11 (0.66) | KIF11MAPTMAPK1NPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL572039 | 0.96 | KIF11 (0.63) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL29370563 | 0.84 | STING1 (0.60) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL30022665 | 0.84 | STING1 (0.60) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL8643080 | 0.84 | STING1 (0.60) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL20348818 | 0.81 | KIF11 (0.46) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL26373210 | 0.80 | KIF11 (0.62) | KIF11MAPTMAPK1NPSR1MEN1 | |
| Ammonia Solution, Strong SCHEMBL29136207 | 0.80 | KIF11 (0.96) | KIF11MAPTMAPK1NPSR1MEN1 | |
| SCHEMBL23166719 | 0.79 | KIF11 (0.56) | KIF11MAPTMAPK1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781234-A | Carboline and carbazole based imaging agents for detecting neurological dysfunction | LILLY CO ELI | 2015-07-15 | — | — | CN | disclosed |