SCHEMBL29370563

SCHEMBL29370563

Cc1ccc2c(=O)c3ccccc3[nH]c2c1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.60
ABCB1 P08183 1/20 0.59
HTT P42858 3/20 0.57
GAA P10253 3/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.57
GLA P06280 2/20 0.57
LMNA P02545 1/20 0.57
HPGD P15428 1/20 0.57
ATM Q13315 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
POLB P06746 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
MAOA P21397 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
MAPT P10636 2/20 0.51
NPC1 O15118 1/20 0.51
PBRM1 Q86U86 1/20 0.51
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30022665 1.00 STING1 (0.60) STING1ABCB1HTTGAAKDM4E
SCHEMBL8643080 1.00 STING1 (0.60) STING1ABCB1HTTGAAKDM4E
SCHEMBL146378 0.85 KIF11 (0.66) STING1ABCB1KDM4EALDH1A1HPGD
SCHEMBL29726990 0.85 KIF11 (0.66) STING1ABCB1KDM4EALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL28022012 0.84 KIF11 (0.63) STING1ABCB1KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL572039 0.84 KIF11 (0.63) STING1ABCB1KDM4EALDH1A1HPGD
SCHEMBL21027577 0.83 HTT (0.53) STING1ABCB1HTTGAAKDM4E
SCHEMBL13425978 0.83 MAOA (0.54) STING1ABCB1HTTGAAKDM4E
SCHEMBL14116119 0.82 KIF11 (0.72) ABCB1HTTGAAKDM4EALDH1A1
SCHEMBL14552258 0.80 ALDH1A1 (0.68) ABCB1HTTGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12329746-B2 AR+breast cancer treatment methods ELLIPSES PHARMA LTD (GB) 2025-06-17 US claimed
US-20250129163-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF AKESO BIOPHARMA, INC. (CN) 2025-04-24 US claimed
US-20250114450-A1 PHARMACEUTICAL COMBINATION CONTAINING ANTI-PD-1-ANTI-VEGFA BISPECIFIC ANTIBODY, AND USE THEREOF AKESO BIOPHARMA, INC. (CN) 2025-04-10 US claimed
US-20250009736-A1 METHODS OF TREATING CANCERS OVEREXPRESSING CARM1 WITH EZH2 INHIBITORS AND A PARP INHIBITOR WISTAR INST (US) 2025-01-09 US claimed
US-20240207234-A1 AR+BREAST CANCER TREATMENT METHODS ELLIPSES PHARMA LTD (GB) 2024-06-27 US claimed
EP-4321537-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF Akeso Biopharma, Inc. (CN) 2024-02-14 EP claimed
WO-2023246247-A1 PHARMACEUTICAL COMPOSITION AND USE THEREOF 中山康方生物医药有限公司 2023-12-28 WO claimed
CN-117257934-A Pharmaceutical composition and use thereof 中山康方生物医药有限公司 2023-12-22 CN claimed
EP-4190819-A1 PHARMACEUTICAL COMBINATION CONTAINING ANTI-PD-1-ANTI-VEGFA BISPECIFIC ANTIBODY, AND USE THEREOF Akeso Biopharma, Inc. (CN) 2023-06-07 EP claimed
CN-115702934-A Combination of an MCL-1 inhibitor and an inhibitor of a member of the DNA damage response pathway 江苏恒瑞医药股份有限公司 2023-02-17 CN claimed
CN-217928281-U Comprehensive sequential hydrogenation control system 上海氢枫能源技术有限公司 2022-11-29 CN claimed
EP-4066827-A1 AR+ BREAST CANCER TREATMENT METHODS Ellipses Pharma Ltd (GB) 2022-10-05 EP claimed
CN-115068603-A Pharmaceutical combination containing anti-PD-1-anti-VEGFA bispecific antibody and application thereof 中山康方生物医药有限公司 2022-09-20 CN claimed
WO-2022188832-A1 PHARMACEUTICAL COMBINATION CONTAINING ANTI-PD-1-ANTI-VEGFA BISPECIFIC ANTIBODY, AND USE THEREOF 中山康方生物医药有限公司 2022-09-15 WO claimed
CN-110907559-B Universal fixed bed catalyst evaluation device 武汉纺织大学 2022-04-08 CN claimed
EP-3474841-B1 AR+ BREAST CANCER TREATMENT METHODS ELLIPSES PHARMA LTD (GB) 2022-03-16 EP claimed
EP-4096651-B1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC (US) 2026-05-27 EP disclosed
CN-122036912-A Cytokine conjugates for the treatment of proliferative and infectious diseases 辛索克斯公司 2026-05-15 CN disclosed
US-20220048906-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2022-02-17 US disclosed
WO-2022025880-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048906-A1 COMPOUNDS AND USES THEREOF VHL, TFEB, BECN1 STING1 659/4885ABCB1 384/4885HTT 377/4885
US-20240207234-A1 AR+BREAST CANCER TREATMENT METHODS BRCA1, AR, PARP6 STING1 1110/4885ABCB1 1275/4885HTT 2105/4885
US-20250009736-A1 METHODS OF TREATING CANCERS OVEREXPRESSING CARM1 WITH EZH2 INHIBITORS AND A PARP INHIBITOR CARM1, EZH2, PRMT1 STING1 2389/4885ABCB1 2007/4885HTT 3725/4885
US-12329746-B2 AR+breast cancer treatment methods BRCA1, AR, PARP6 STING1 1110/4885ABCB1 1275/4885HTT 2105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.