SCHEMBL1463885

SCHEMBL1463885

CC1(C(=O)O)CNCCO1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15571990 0.85
SCHEMBL27902367 0.85
Hydrochloric Acid SCHEMBL15573753 0.83
SCHEMBL11479401 0.82 PKM (0.34)
SCHEMBL27619704 0.79
SCHEMBL27506919 0.79
SCHEMBL27638823 0.79
SCHEMBL19987657 0.77 ALDH1A1 (0.30)
Hydrochloric Acid SCHEMBL15415561 0.77
Acrylic Acid SCHEMBL28838873 0.77 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0199490-A1 Penem derivatives FARMITALIA CARLO ERBA S.r.l. (IT) 1986-10-29 EP claimed
CN-111032034-B Spiro compounds and methods of making and using the same H.隆德贝克有限公司 2023-05-02 CN disclosed
CN-109496213-B Spiro compounds and methods of making and using the same H.隆德贝克有限公司 2022-03-04 CN disclosed
EP-2688872-A1 AMIDOPYRAZOLE INHIBITORS OF INTERLEUKIN RECEPTOR-ASSOCIATED KINASES Merck Sharp & Dohme Corp. (US) 2014-01-29 EP disclosed
WO-2012129258-A1 AMIDOPYRAZOLE INHIBITORS OF INTERLEUKIN RECEPTOR-ASSOCIATED KINASES MERCK SHARP & DOHME CORP. (US) 2012-09-27 WO disclosed
EP-2473499-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES Novartis AG (CH) 2012-07-11 EP disclosed
WO-2011026911-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES NOVARTIS AG (CH) 2011-03-10 WO disclosed
CN-1774435-A 5-membered heterocyclic derivative DAIICHI SEIYAKU CO (JP) 2006-05-17 CN disclosed
EP-0226267-B1 OXA-, THIA- AND DIAZABICYCLOALKANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS BEECHAM GROUP PLC (GB) 1993-01-13 EP disclosed
US-4883874-A Azabicyclic intermediates BEECHAM GROUP PLC. OF BEECHAM HOUSE (GB) 1989-11-28 US disclosed
US-4826839-A GASTROINTESTINAL DISORDERS, HEADACHES BEECHAM GROUP P.L.C. (GB) 1989-05-02 US disclosed