Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965463 | 0.76 | EPHX2 (0.40) | EPHX2HSD11B1POLBMEN1KMT2A | |
| SCHEMBL9965476 | 0.70 | HRH1 (0.42) | HSD11B1POLBRIPK1TACR1 | |
| SCHEMBL18711673 | 0.66 | CCNC (0.49) | HSD11B1POLBRIPK1MEN1NPC1 | |
| SCHEMBL24011067 | 0.66 | RIPK1 (0.68) | EPHX2HSD11B1POLBRIPK1MEN1 | |
| SCHEMBL9201803 | 0.64 | TACR1 (0.54) | RIPK1TACR1 | |
| SCHEMBL9201806 | 0.64 | TACR1 (0.54) | RIPK1TACR1 | |
| SCHEMBL9965374 | 0.63 | PKM (0.38) | EPHX2MEN1KMT2A | |
| SCHEMBL20012078 | 0.62 | RIPK1 (0.48) | KDM1ARIPK1 | |
| SCHEMBL29115969 | 0.62 | RIPK1 (0.48) | KDM1ARIPK1 | |
| SCHEMBL30661786 | 0.62 | KDM1A (0.45) | KDM1ARIPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |