Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641004 | 0.76 | LMNA (0.65) | ALDH1A1LMNASMN1; SMN2NSD2MAPK3 | |
| SCHEMBL642366 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2NSD2MAPK3 | |
| SCHEMBL30352893 | 0.70 | EPHX2 (0.55) | ALDH1A1NSD2JAK1MAPTBRD4 | |
| SCHEMBL25009521 | 0.69 | MAPT (0.49) | LMNANSD2MAPK3JAK1MAPT | |
| SCHEMBL30271400 | 0.69 | NSD2 (0.49) | LMNASMN1; SMN2NSD2MAPK3JAK1 | |
| SCHEMBL16407626 | 0.69 | MAPT (0.55) | NSD2MAPK3JAK1MAPTBRD4 | |
| SCHEMBL9965472 | 0.69 | NSD2 (0.49) | NSD2MAPK3JAK1MAPTBRD4 | |
| SCHEMBL642920 | 0.69 | NSD2 (0.49) | LMNASMN1; SMN2NSD2MAPK3JAK1 | |
| SCHEMBL9965473 | 0.67 | TSHR (0.54) | ALDH1A1SMN1; SMN2NSD2JAK1MAPT | |
| SCHEMBL25011533 | 0.67 | NSD2 (0.50) | NSD2MAPK3JAK1MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |