SCHEMBL1463983

SCHEMBL1463983

OCCOCCN(CCOCCO)CCOCCO

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
MAPK1 P28482 1/20 0.62
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.43
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12907797 0.97 MEN1 (0.65) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL30359262 0.97 TSHR (0.59) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL63684 0.97 MEN1 (0.65) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL2593277 0.94 TSHR (0.56) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL522377 0.94 TSHR (0.56) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL389508 0.92 MEN1 (0.58) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL7771250 0.89 TSHR (0.50) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL2740844 0.89 TSHR (0.50) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL2057385 0.88 TSHR (0.56) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL4294793 0.88 TSHR (0.44) TSHRMAPK1MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9119774-B2 Self-healing dental restorative formulations and related methods PREMIER DENTAL PRODUCTS COMPANY (US) 2015-09-01 US claimed
US-20110071234-A1 Self-Healing dental restorative formulations and related methods FIDELITY DIRECT LENDING LLC, AS ADMINISTRATIVE AGENT 2011-03-24 US claimed
EP-1211346-B1 Non-felting wool and process for giving an anti-felting finish BAYER CHEMICALS AG (DE) 2004-07-14 EP claimed
EP-1437437-A2 Anti-felting treatment of keratinous fibres Bayer Chemicals AG (DE) 2004-07-14 EP claimed
EP-1367172-A2 Dyed, non-felting keratinous fibres and method for the manufacture BAYER AG (DE) 2003-12-03 EP claimed
US-6464768-B1 THERMAL RECORDING MEDIA; JET PRINTER INKS PRODUCING IMAGES HAVING HIGH OPTICAL DENSITY, PHOTOSTABILITY, RESOLUTION, WATER AND ABRASION RESISTANCE CLARIANT GMBH (DE) 2002-10-15 US claimed
EP-1211346-A1 Non-felting wool and process for giving an anti-felting finish BAYER AG (DE) 2002-06-05 EP claimed
EP-0971003-B1 Water soluble black stilbene dyes, their preparation and use CLARIANT GMBH (DE) 2001-10-17 EP claimed
WO-2001034895-A2 ANTIFELTING FINISHED WOOL AND ANTIFELTING FINISHING METHOD BAYER AKTIENGESELLSCHAFT (DE) 2001-05-17 WO claimed
EP-0971003-A1 Water soluble black stilbene dyes, their preparation and use Clariant GmbH (DE) 2000-01-12 EP claimed
US-4757105-A Reacting water with organic polyisocyanate in the presence of an amine-containing emulsion stabilizer BAYER AKTIENGESELLSCHAFT (DE) 1988-07-12 US claimed
EP-0270804-A1 Process for the preparation of finely divided polyisocyanates containing urea groups BAYER AG (DE) 1988-06-15 EP claimed
EP-0063066-B1 PROCESS FOR THE ISOMERIZATION OF BROMOHALOGEN BENZENES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-06-20 EP claimed
US-4362855-A Polymerization of polysiloxanes RHONE-POULENC INDUSTRIES (FR) 1982-12-07 US claimed
EP-0015860-B1 PROCESS FOR THE PREPARATION OF POLYGLYCIDYL ETHERS OF POLYPHENOLS RHONE-POULENC CHIMIE DE BASE (FR) 1982-10-13 EP claimed
US-4273915-A TRIS/OXYALKYL/AMINE, APROTIC SOLVENT, EPOXY RESIN RHONE-POULENC INDUSTRIES (FR) 1981-06-16 US claimed
EP-0002148-B1 COMPOSITIONS CONTAINING AMINOALKOXYAMINES, AND PROCESSES FOR THEIR PREPARATION RHONE-POULENC INDUSTRIES (FR) 1980-12-10 EP claimed
US-4219626-A Accelerators for radical polymerization reactions with initiators free from peroxide groups BAYER AKTIENGESELLSCHAFT (DE) 1980-08-26 US claimed
EP-0002147-B1 PROCESS FOR THE PREPARATION OF TRIS(3-OXA-5-HYDROXY-PENTYL)AMINE RHONE-POULENC INDUSTRIES (FR) 1980-07-23 EP claimed
US-4087245-A Process for the preparation of concentrated solutions of anionic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-05-02 US claimed