SCHEMBL522377

SCHEMBL522377

OCCOCCN(CCO)CCO

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
MAPK1 P28482 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 1/20 0.39
MAPT P10636 3/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2593277 1.00 TSHR (0.56) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL389508 0.97 MEN1 (0.58) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL1463983 0.94 TSHR (0.62) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL4294793 0.94 TSHR (0.44) TSHRMAPK1MEN1KMT2ABLM
Trolamine SCHEMBL4633175 0.94 TSHR (0.62) TSHRMAPK1MEN1KMT2ABLM
Trolamine SCHEMBL16685318 0.92 MEN1 (0.65) TSHRMAPK1MEN1KMT2ABLM
Trolamine SCHEMBL27779564 0.92 TSHR (0.59) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL63684 0.92 MEN1 (0.65) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL12907797 0.92 MEN1 (0.65) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL12646242 0.92 BLM (0.48) TSHRMAPK1MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580887-B2 High-functionality polyisocyanates containing urethane groups BASF SE (DE) 2013-11-12 US claimed
EP-2598549-A1 HIGH-FUNCTIONALITY POLYISOCYANATES HAVING URETHANE GROUPS BASF SE (DE) 2013-06-05 EP claimed
US-20120029144-A1 HIGH-FUNCTIONALITY POLYISOCYANATES CONTAINING URETHANE GROUPS BASF SE (DE) 2012-02-02 US claimed
WO-2012013681-A1 HIGH-FUNCTIONALITY POLYISOCYANATES HAVING URETHANE GROUPS BASF SE (DE) 2012-02-02 WO claimed
JP-4537580-B2 2010-09-01 JP claimed
EP-1211238-B1 Process for the preparation of ethanolamines BASF AG (DE) 2004-06-30 EP claimed
EP-1114023-B1 PROCESS FOR PREPARING CARBOXYLIC ACIDS DOW AGROSCIENCES LLC (US) 2004-05-26 EP claimed
US-20020115890-A1 Process for the preparation of ethanolamines BASF AKTIENGESELLSCHAFT (DE) 2002-08-22 US claimed
JP-2002524548-A 2002-08-06 JP claimed
EP-1211238-A1 Process for the preparation of ethanolamines BASF AKTIENGESELLSCHAFT (DE) 2002-06-05 EP claimed
CN-1318047-A Process for preparing carboxylic acids DOW AGROSCIENCES LLC (US) 2001-10-17 CN claimed
US-20010008948-A1 Process for preparing carboxylic acids RINGER JAMES W (US) 2001-07-19 US claimed
EP-1114023-A1 PROCESS FOR PREPARING CARBOXYLIC ACIDS Dow AgroSciences LLC (US) 2001-07-11 EP claimed
US-6229045-B1 CARBOXYLATION OF PRIMARY ALIPHATIC ALCOHOLS IN ALKALINE SOLUTION VIA CONTACTING WITH A CATALYST COMPRISING COBALT, COPPER, CERIUM, IRON, ZINC, AND/OR ZIRCONIUM DOW AGROSCIENCES LLC 2001-05-08 US claimed
WO-2000015601-A1 PROCESS FOR PREPARING CARBOXYLIC ACIDS DOW AGROSCIENCES LLC (US) 2000-03-23 WO claimed
EP-4711436-A1 DETERGENT COMPOSITION WITH PEPTIDES AND PROTEINS Henkel AG & Co. KGaA (DE) 2026-03-18 EP disclosed
WO-2026044184-A1 LIQUID DETERGENTS WITH IMPROVED MILDNESS FOR SENSITIVE SKIN HENKEL AG & CO. KGAA (DE) 2026-02-26 WO disclosed
US-5214738-A POSITIVE COEFFICIENT THIN-FILM THERMISTOR MITSUI TOATSU CHEMICALS, INC. (JP) 1993-05-25 US disclosed
EP-0438593-A1 POSITIVE COEFFICIENT THIN-FILM THERMISTOR MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-07-31 EP disclosed
US-4165293-A Solid transparent cleanser AMWAY CORPORATION (US) 1979-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029144-A1 HIGH-FUNCTIONALITY POLYISOCYANATES CONTAINING URETHANE GROUPS UROD, DDT, UGT1A3 TSHR 4039/4885MAPK1 3847/4885MEN1 2188/4885
US-20010008948-A1 Process for preparing carboxylic acids ADH1A, ADH1C, ADH5 TSHR 1913/4885MAPK1 1571/4885MEN1 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.