SCHEMBL389508

SCHEMBL389508

OCCOCCOCCOCCN(CCO)CCO

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
TSHR P16473 2/20 0.53
MAPK1 P28482 1/20 0.53
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.30
APP P05067 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522377 0.97 TSHR (0.56) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL2593277 0.97 TSHR (0.56) MEN1KMT2ATSHRMAPK1BLM
Trolamine SCHEMBL16685318 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL12907797 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL63684 0.95 MEN1 (0.65) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL12646242 0.95 BLM (0.48) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL1463983 0.92 TSHR (0.62) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL4294793 0.92 TSHR (0.44) MEN1KMT2ATSHRMAPK1BLM
Trolamine SCHEMBL4633175 0.92 TSHR (0.62) MEN1KMT2ATSHRMAPK1BLM
SCHEMBL30359262 0.89 TSHR (0.59) MEN1KMT2ATSHRMAPK1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101731-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION 2012-01-24 US disclosed
US-20100199443-A1 YELLO ANIONIC DISAZO DYES LENNARTZ MICHAEL 2010-08-12 US disclosed
US-7723494-B2 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20080114158-A1 Yellow anionic disazo dyes LENNARTZ MICHAEL 2008-05-15 US disclosed
US-7351808-B2 Anionic monoazo dyes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-01 US disclosed
US-7341607-B2 Based on diaminobenzanilides or, more specifically (aminobenzoylamino),(sulfo-),(methoxy)anilines; stable aqueous solutions;nonbleeding/colorfastness; excellent degrees of exhaustion with high colour strength; dyeing natural or synthetic materials, particularly, paper; neutral or greenish-yellow hues CIBA SPECIALTY CHEMICALS CORP. (US) 2008-03-11 US disclosed
EP-1525267-B1 ANIONIC MONOAZO DYES CIBA SC HOLDING AG (CH) 2007-03-21 EP disclosed
US-20050256305-A1 Anionic monoazo dyes CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050172420-A1 Yellow anionic disazo dyes CIBA SPECIALTY CHEMICALS CORP. 2005-08-11 US disclosed
EP-1525267-A1 ANIONIC MONOAZO DYES Ciba SC Holding AG (CH) 2005-04-27 EP disclosed
EP-1509574-A1 YELLOW ANIONIC DISAZO DYES Ciba SC Holding AG (CH) 2005-03-02 EP disclosed
WO-2004013233-A1 ANIONIC MONOAZO DYES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-02-12 WO disclosed
WO-2003104333-A1 YELLOW ANIONIC DISAZO DYES CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) 2003-12-18 WO disclosed
US-5545725-A FOR DYEING PAPER CIBA-GEIGY CORPORATION (US) 1996-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050172420-A1 Yellow anionic disazo dyes IK, CYB5R3, DCXR MEN1 3799/4885KMT2A 1359/4885TSHR 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.