Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049689 | 0.83 | HDAC3 (0.31) | — | |
| SCHEMBL8683439 | 0.76 | TAAR1 (0.54) | TAAR1HTR1DMEN1RAD52RECQL | |
| SCHEMBL6634488 | 0.73 | HDAC3 (0.39) | TAAR1 | |
| SCHEMBL8390342 | 0.72 | HTT (0.41) | TAAR1MAPTNOS3NOS1NOS2 | |
| SCHEMBL6284487 | 0.72 | TAAR1 (0.44) | TAAR1MEN1RAD52RECQLKMT2A | |
| SCHEMBL6963717 | 0.71 | TAAR1 (0.52) | TAAR1HTR1DMEN1RAD52RECQL | |
| Hydrochloric Acid SCHEMBL12818395 | 0.70 | KMT2A (0.46) | TAAR1MEN1RAD52RECQLKMT2A | |
| SCHEMBL8090926 | 0.70 | ALDH1A1 (0.34) | KDM4E | |
| SCHEMBL5410669 | 0.69 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL15787657 | 0.68 | NOS1 (0.39) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |