Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149120 | 0.84 | HTT (0.38) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL22385039 | 0.78 | HTT (0.38) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL6634488 | 0.78 | HDAC3 (0.39) | CA12CA1CA2CA7CA13 | |
| SCHEMBL30952527 | 0.75 | CA1 (0.40) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1032872 | 0.75 | CA1 (0.40) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL11049689 | 0.74 | HDAC3 (0.31) | HDAC3HDAC6CES2CES1 | |
| SCHEMBL8090926 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HDAC3HDAC6CES2CES1 | |
| SCHEMBL11140623 | 0.73 | HTT (0.50) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL11140303 | 0.73 | HTT (0.41) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL14640286 | 0.72 | TAAR1 (0.41) | MAPTNOS3NOS1NOS2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912492-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998002409-A1 | METHOD FOR PREPARING HALOGENATED 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE DERIVATIVES | RHODIA CHIMIE (FR) | 1998-01-22 | — | — | WO | disclosed |