Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957384 | 0.87 | S1PR5 (0.46) | KCNH2HRH3POLBALDH1A1 | |
| SCHEMBL14944939 | 0.86 | KCNH2 (0.40) | KCNH2HRH3 | |
| SCHEMBL13957383 | 0.82 | KCNH2 (0.43) | L3MBTL1KCNH2HRH3 | |
| SCHEMBL14948179 | 0.82 | L3MBTL1 (0.49) | L3MBTL1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6952343 | 0.79 | L3MBTL1 (0.49) | L3MBTL1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1119544 | 0.78 | NEK2 (0.35) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL22049970 | 0.77 | PRMT3 (0.44) | KCNH2HRH3POLB | |
| SCHEMBL580852 | 0.76 | PSEN1 (0.49) | L3MBTL1POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27696116 | 0.76 | AKR1C3 (0.47) | L3MBTL1KCNH2HRH3AGTR2 | |
| SCHEMBL5517445 | 0.76 | L3MBTL1 (0.46) | L3MBTL1POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |