Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 5/20 | 0.46 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640598 | 0.87 | KAT2B (0.45) | KAT2BMAPTHSD17B10HTR2AHTR2C | |
| SCHEMBL80967 | 0.84 | KAT2B (0.58) | KAT2BALDH1A1PKMMAPTG6PD | |
| Hydrochloric Acid SCHEMBL9517520 | 0.82 | KAT2B (0.56) | KAT2BALDH1A1PKMMAPTG6PD | |
| SCHEMBL678175 | 0.77 | KAT2B (0.58) | KAT2BMAPT | |
| SCHEMBL14640438 | 0.77 | KAT2B (0.49) | KAT2BALDH1A1PKMMAPTG6PD | |
| SCHEMBL5593629 | 0.76 | KAT2B (0.49) | KAT2BALDH1A1PKMMAPTG6PD | |
| SCHEMBL2109583 | 0.75 | KAT2B (0.56) | KAT2BALDH1A1PKMMAPTG6PD | |
| SCHEMBL14640601 | 0.75 | KAT2B (0.57) | KAT2BALDH1A1 | |
| SCHEMBL5593712 | 0.74 | KAT2B (0.55) | KAT2BALDH1A1PKMMAPTG6PD | |
| SCHEMBL14640437 | 0.71 | KAT2B (0.41) | KAT2BALDH1A1PKMMAPTG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001932-A2 | SUBSTITUTED ISOTHIAZOLONES AS INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |