SCHEMBL678175

SCHEMBL678175

O=c1cc(Cl)sn1Cc1ccc(Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 11/20 0.58
EP300 Q09472 1/20 0.45
CREBBP Q92793 1/20 0.45
KAT2A Q92830 1/20 0.45
IDO1 P14902 2/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
RGS4 P49798 2/20 0.39
RGS8 P57771 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3655957 0.89 ALDH1A1 (0.57) KAT2BEP300CREBBPKAT2AMAPT
SCHEMBL6931122 0.86 KAT2B (0.53) KAT2BEP300CREBBPKAT2A
SCHEMBL5593712 0.85 KAT2B (0.55) KAT2BEP300CREBBPKAT2ACA12
SCHEMBL80967 0.85 KAT2B (0.58) KAT2BMAPTRGS4RGS8
Hydrochloric Acid SCHEMBL9517520 0.83 KAT2B (0.56) KAT2BMAPTRGS4RGS8
SCHEMBL14640429 0.81 KAT2B (0.50) KAT2BCA12CA1CA9MAPT
SCHEMBL14640440 0.81 KAT2B (0.50) KAT2BEP300CREBBPKAT2ACA12
SCHEMBL5593629 0.80 KAT2B (0.49) KAT2BMAPTKMT2A
SCHEMBL5593574 0.77 KAT2B (0.43) KAT2B
SCHEMBL14640376 0.77 KAT2B (0.46) KAT2BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions GIRONDA KEVIN F (US) 2002-09-12 US claimed
US-5912286-A Silicone-containing fluoropolymers for controlled release of organic leachants THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-06-15 US claimed
EP-0762955-A4 ANTIFOULING AND FOUL-RELEASE COATINGS US HEALTH (US) 1998-01-07 EP claimed
EP-0762955-A1 ANTIFOULING AND FOUL-RELEASE COATINGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) 1997-03-19 EP claimed
WO-1995032862-A1 ANTIFOULING AND FOUL-RELEASE COATINGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-12-07 WO claimed
US-5145501-A Fungicides, algicides, bactericides ROHM AND HAAS COMPANY (US) 1992-09-08 US claimed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP claimed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US claimed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP claimed
US-4127687-A PAINTING WITH ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1978-11-28 US claimed
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity SPOGEN BIOTECH INC. (US) 2026-04-14 US disclosed
WO-2025242701-A1 SEED TREATMENT COMPOSITIONS BASF SE (DE) 2025-11-27 WO disclosed
US-20250351825-A1 AGRICULTURAL COMPOSITIONS FOR PROTECTING PLANTS AGAINST ABIOTIC STRESSORS SPOGEN BIOTECH INC (US) 2025-11-20 US disclosed
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS OHIO STATE INNOVATION FOUNDATION (US) 2025-10-23 US disclosed
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US disclosed
EP-0147970-B1 MICROBIOCIDAL OR ANTIMICROBIAL BIOMEDICAL DEVICES ROHM AND HAAS COMPANY (US) 1989-03-01 EP disclosed
US-4542169-A Biomedical devices containing isothiazolones to control bacteria growth ROHM AND HAAS COMPANY (US) 1985-09-17 US disclosed
EP-0147970-A1 Microbiocidal or antimicrobial biomedical devices ROHM AND HAAS COMPANY (US) 1985-07-10 EP disclosed
US-4165318-A AGAINST CHEMICAL DECOMPOSITION OF THE 3-ISOTHIAZOLONE MILDEW CONTROLLING AGENT ROHM AND HAAS COMPANY (US) 1979-08-21 US disclosed
US-4129448-A A 3-ISOTHIAZOLONE ROHM AND HAAS COMPANY (US) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity MAX, VIP, MRTO4 KAT2B 2768/4885EP300 3062/4885CREBBP 1569/4885
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS ARGLU1, PHAX, VMA21 KAT2B 3403/4885EP300 4513/4885CREBBP 3625/4885
US-20020128311-A1 Halocyanoacetamide antimicrobial compositions HDHD5, DGKI, DAGLA KAT2B 1127/4885EP300 218/4885CREBBP 1323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.