SCHEMBL80967

SCHEMBL80967

O=c1cc(Cl)sn1Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 8/20 0.58
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
G6PD P11413 1/20 0.55
PKM P14618 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
HTT P42858 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
GSK3B P49841 6/20 0.51
GSK3A P49840 4/20 0.51
CASP3 P42574 1/20 0.50
F2 P00734 1/20 0.45
PLG P00747 1/20 0.45
ELANE P08246 1/20 0.45
CTSG P08311 1/20 0.45
CMA1 P23946 1/20 0.45
CTRC Q99895 1/20 0.45
ALKBH5 Q6P6C2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9517520 0.98 KAT2B (0.56) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL2109583 0.86 KAT2B (0.56) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL678175 0.85 KAT2B (0.58) KAT2BMAPTRGS4RGS8
SCHEMBL14640376 0.84 KAT2B (0.46) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL14640438 0.84 KAT2B (0.49) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL5593775 0.83 KAT2B (0.49) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL5593629 0.83 KAT2B (0.49) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL5593712 0.81 KAT2B (0.55) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL14640434 0.81 KAT2B (0.46) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL14640437 0.79 KAT2B (0.41) KAT2BALDH1A1MAPTG6PDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-20160290036-A1 HEAT-SHIELDING MATERIAL AND WINDOW GLASS FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160290036-A1 HEAT-SHIELDING MATERIAL AND WINDOW GLASS FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-7939554-B2 Of Src homology protein tyrosine phosphatase 1; phenyl isothiazolones or a benzo-1,4-quinone; antineoplastic agents; immunostimulants inducing a cytokine response; side effect reduction THE CLEVELAND CLINIC FOUNDATION (US) 2011-05-10 US disclosed
US-7939554-B2 Of Src homology protein tyrosine phosphatase 1; phenyl isothiazolones or a benzo-1,4-quinone; antineoplastic agents; immunostimulants inducing a cytokine response; side effect reduction THE CLEVELAND CLINIC FOUNDATION (US) 2011-05-10 US disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042334-A2 Method of producing heat-sensitive transfer image-receiving sheet Fujifilm Corporation (JP) 2009-04-01 EP disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
EP-0031705-A1 Substituted 3-isothiazolones, salts and metal salt complexes thereof, compositions containing them and their use for combating bacteria, algae and fungi ROHM AND HAAS COMPANY (US) 1981-07-08 EP disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4127687-A PAINTING WITH ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1978-11-28 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed