SCHEMBL2109583

SCHEMBL2109583

O=c1cc(Cl)sn1CCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 8/20 0.56
GSK3B P49841 3/20 0.56
CASP3 P42574 1/20 0.50
PRKCA P17252 1/20 0.49
ALDH1A1 P00352 2/20 0.45
MAPT P10636 1/20 0.45
G6PD P11413 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH2 P05091 1/20 0.44
ALDH3A1 P30838 1/20 0.44
GSK3A P49840 1/20 0.43
MGLL Q99685 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6931122 0.87 KAT2B (0.53) KAT2BGSK3BPRKCAALDH1A1ALDH2
SCHEMBL80967 0.86 KAT2B (0.58) KAT2BGSK3BCASP3PRKCAALDH1A1
Hydrochloric Acid SCHEMBL9517520 0.84 KAT2B (0.56) KAT2BGSK3BCASP3PRKCAALDH1A1
SCHEMBL9854210 0.81 KAT2B (0.50) KAT2BCASP3ALDH1A1
SCHEMBL11266445 0.78 CASP3 (0.48) GSK3BCASP3PRKCAALDH1A1MAPT
SCHEMBL14640376 0.75 KAT2B (0.46) KAT2BGSK3BCASP3ALDH1A1MAPT
SCHEMBL9565202 0.74 KAT2B (0.79) KAT2BALDH1A1MAPTG6PDPKM
SCHEMBL8430762 0.73 CASP3 (0.58) KAT2BGSK3BCASP3PRKCAALDH1A1
SCHEMBL11189889 0.73 KAT2B (0.77) KAT2BGSK3BALDH1A1G6PDHPGD
SCHEMBL9234887 0.73 KAT2B (0.61) KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006001558-A1 HIGH SELECTIVITY CMP SLURRY COMPOSITION FOR STI PROCESS IN SEMICONDUCTOR MANUFACTURE CHEIL INDUSTIRES INC. (KR) 2006-01-05 WO claimed
US-5912286-A Silicone-containing fluoropolymers for controlled release of organic leachants THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-06-15 US claimed
EP-0762955-A4 ANTIFOULING AND FOUL-RELEASE COATINGS US HEALTH (US) 1998-01-07 EP claimed
EP-0762955-A1 ANTIFOULING AND FOUL-RELEASE COATINGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) 1997-03-19 EP claimed
WO-1995032862-A1 ANTIFOULING AND FOUL-RELEASE COATINGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-12-07 WO claimed
US-5073582-A MILDEW RESISTANT PAINT COMPOSITIONS COMPRISING AN ISOTHIAZOLONE AND A WATER-INSOLUBLE COPPER COMPOUND, ARTICLES, AND METHODS ROHM AND HAAS COMPANY (US) 1991-12-17 US claimed
EP-0408215-A1 Mildew resistant paint compositions ROHM AND HAAS COMPANY (US) 1991-01-16 EP claimed
US-4127687-A PAINTING WITH ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1978-11-28 US claimed
US-20250154366-A1 A PAINT COMPOSITION VECOR IP HOLDINGS LIMITED (CN) 2025-05-15 US disclosed
EP-4479480-A1 A PAINT COMPOSITION Vecor IP Holdings Limited (CN) 2024-12-25 EP disclosed
EP-4227372-A1 A WHITE PAINT COMPOSITION Vecor IP Holdings Limited (HK) 2023-08-16 EP disclosed
WO-2023077174-A1 A PAINT COMPOSITION VECOR IP HOLDINGS LIMITED (CN) 2023-05-04 WO disclosed
US-8157877-B2 Chemical mechanical polishing aqueous dispersion, chemical mechanical polishing method, and kit for preparing chemical mechanical polishing aqueous dispersion JSR CORPORATION (JP) 2012-04-17 US disclosed
US-20090325323-A1 AQUEOUS DISPERSION FOR CHEMICAL MECHANICAL POLISHING, PRODUCTION METHOD THEREOF, AND CHEMICAL MECHANICAL POLISHING METHOD JSR CORPORATION (JP) 2009-12-31 US disclosed
EP-0182566-A2 Method for processing lightsensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-05-28 EP disclosed
EP-0031705-B1 SUBSTITUTED 3-ISOTHIAZOLONES, SALTS AND METAL SALT COMPLEXES THEREOF, COMPOSITIONS CONTAINING THEM AND THEIR USE FOR COMBATING BACTERIA, ALGAE AND FUNGI ROHM AND HAAS COMPANY (US) 1984-03-21 EP disclosed
US-4310590-A BACTERICIDES, FUNGICIDES ROHM AND HAAS COMPANY (US) 1982-01-12 US disclosed
EP-0031705-A1 Substituted 3-isothiazolones, salts and metal salt complexes thereof, compositions containing them and their use for combating bacteria, algae and fungi ROHM AND HAAS COMPANY (US) 1981-07-08 EP disclosed
US-4165318-A AGAINST CHEMICAL DECOMPOSITION OF THE 3-ISOTHIAZOLONE MILDEW CONTROLLING AGENT ROHM AND HAAS COMPANY (US) 1979-08-21 US disclosed
US-4129448-A A 3-ISOTHIAZOLONE ROHM AND HAAS COMPANY (US) 1978-12-12 US disclosed