Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640434 | 0.77 | KAT2B (0.46) | KAT2BMAPTALDH1A1G6PDPKM | |
| SCHEMBL5593772 | 0.76 | KAT2B (0.42) | KAT2B | |
| SCHEMBL80967 | 0.75 | KAT2B (0.58) | KAT2BMAPTALDH1A1G6PDPKM | |
| SCHEMBL14640401 | 0.74 | FFAR1 (0.49) | KAT2BL3MBTL1GRM5IDH1 | |
| SCHEMBL14640403 | 0.74 | IDH1 (0.45) | KAT2BL3MBTL1HRH3IDH1 | |
| SCHEMBL14640594 | 0.74 | FFAR1 (0.49) | KAT2BL3MBTL1MEN1KMT2AGRM5 | |
| Hydrochloric Acid SCHEMBL9517520 | 0.74 | KAT2B (0.56) | KAT2BMAPTALDH1A1G6PDPKM | |
| SCHEMBL5593775 | 0.74 | KAT2B (0.49) | KAT2BMAPTALDH1A1G6PDPKM | |
| SCHEMBL21119439 | 0.73 | FOLH1 (0.41) | HRH3 | |
| SCHEMBL14640440 | 0.72 | KAT2B (0.50) | KAT2BMAPTALDH1A1G6PDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001932-A2 | SUBSTITUTED ISOTHIAZOLONES AS INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |