Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CLPP | Q16740 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640401 | 0.85 | FFAR1 (0.49) | IDH1L3MBTL1KAT2B | |
| SCHEMBL80967 | 0.75 | KAT2B (0.58) | KAT2B | |
| SCHEMBL14640430 | 0.74 | KAT2B (0.41) | IDH1L3MBTL1KAT2BHRH3 | |
| Hydrochloric Acid SCHEMBL9517520 | 0.74 | KAT2B (0.56) | KAT2B | |
| SCHEMBL2153847 | 0.73 | HRH3 (0.59) | IDH1CYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL678175 | 0.72 | KAT2B (0.58) | KAT2BCREBBP | |
| SCHEMBL4196662 | 0.72 | HRH3 (0.54) | IDH1CYP19A1CYP11B1CYP11B2HRH3 | |
| SCHEMBL14640440 | 0.72 | KAT2B (0.50) | KAT2BCREBBP | |
| SCHEMBL5593775 | 0.71 | KAT2B (0.49) | KAT2B | |
| SCHEMBL481239 | 0.70 | HRH3 (0.49) | IDH1SNCACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001932-A2 | SUBSTITUTED ISOTHIAZOLONES AS INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |