Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 13/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.32 |
| ▸ | USP4 | Q13107 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678175 | 0.81 | KAT2B (0.58) | KAT2BCA12CA1CA9MAPT | |
| SCHEMBL5593787 | 0.78 | KAT2B (0.47) | KAT2BCA12CA1CA9EP300 | |
| SCHEMBL80967 | 0.78 | KAT2B (0.58) | KAT2BALDH1A1MAPTG6PDPKM | |
| Hydrochloric Acid SCHEMBL9517520 | 0.76 | KAT2B (0.56) | KAT2BALDH1A1MAPTG6PDPKM | |
| SCHEMBL14640594 | 0.75 | FFAR1 (0.49) | KAT2B | |
| SCHEMBL14640429 | 0.74 | KAT2B (0.50) | KAT2BCA12CA1CA9ALDH1A1 | |
| SCHEMBL5593629 | 0.73 | KAT2B (0.49) | KAT2BALDH1A1MAPTG6PDPKM | |
| SCHEMBL3655957 | 0.72 | ALDH1A1 (0.57) | KAT2BALDH1A1MAPTG6PDPKM | |
| SCHEMBL14640430 | 0.72 | KAT2B (0.41) | KAT2BALDH1A1MAPTG6PDPKM | |
| SCHEMBL14640376 | 0.71 | KAT2B (0.46) | KAT2BALDH1A1MAPTG6PDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001932-A2 | SUBSTITUTED ISOTHIAZOLONES AS INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |