Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 9/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593916 | 0.88 | KAT2B (0.47) | KAT2BKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL5593840 | 0.79 | KAT2B (0.49) | KAT2BKMT2AMEN1F10ALDH1A1 | |
| SCHEMBL80967 | 0.77 | KAT2B (0.58) | KAT2BMAPTTDP1ALDH1A1G6PD | |
| Hydrochloric Acid SCHEMBL9517520 | 0.76 | KAT2B (0.56) | KAT2BMAPTTDP1ALDH1A1G6PD | |
| SCHEMBL5593775 | 0.76 | KAT2B (0.49) | KAT2BMAPTTDP1ALDH1A1G6PD | |
| SCHEMBL5917410 | 0.74 | LMNA (0.50) | KAT2BKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL5917409 | 0.74 | LMNA (0.50) | KAT2BKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL14640402 | 0.74 | LMNA (0.50) | KAT2BKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL14640434 | 0.73 | KAT2B (0.46) | KAT2BKMT2AMAPTMEN1TDP1 | |
| SCHEMBL14640438 | 0.73 | KAT2B (0.49) | KAT2BKMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001932-A2 | SUBSTITUTED ISOTHIAZOLONES AS INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |