Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640423 | 0.86 | RAB9A (0.55) | RAB9AHDAC1KDM1ASCN2ASCN10A | |
| SCHEMBL17806746 | 0.82 | MKNK1 (0.52) | HDAC1KDM1ASCN10AXDH | |
| SCHEMBL14615882 | 0.80 | RAB9A (0.68) | RAB9AHDAC1SMN1; SMN2NPC1TP53 | |
| SCHEMBL14640455 | 0.79 | MAPK1 (0.61) | RAB9AHDAC1KDM1ASMN1; SMN2NPC1 | |
| SCHEMBL13918750 | 0.79 | KDM4E (0.57) | RAB9ASMN1; SMN2NPC1HPGDL3MBTL1 | |
| SCHEMBL14640456 | 0.79 | BRAF (0.53) | RAB9AHDAC1KDM1ASMN1; SMN2MAPK1 | |
| SCHEMBL14640454 | 0.78 | HDAC1 (0.78) | RAB9AHDAC1KDM1ASCN2ASCN10A | |
| SCHEMBL14640457 | 0.77 | KCNK9 (0.59) | RAB9ASCN10ASMN1; SMN2NPC1 | |
| SCHEMBL14640449 | 0.77 | KMT2A (0.53) | RAB9ASMN1; SMN2NPC1HPGDMEN1 | |
| SCHEMBL1758395 | 0.76 | MKNK1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |