Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640428 | 0.89 | ABL1 (0.49) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3456068 | 0.82 | RAB9A (0.71) | KMT2AMEN1EPHX1EPHX2RAB9A | |
| SCHEMBL10212094 | 0.82 | RAB9A (0.71) | KMT2AMEN1EPHX1EPHX2RAB9A | |
| SCHEMBL14640427 | 0.81 | TSHR (0.53) | KMT2AMEN1KDM4ERAB9ANPC1 | |
| SCHEMBL5606272 | 0.81 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL13483865 | 0.80 | RAB9A (0.68) | KMT2AMEN1EPHX1EPHX2RAB9A | |
| SCHEMBL17806746 | 0.79 | MKNK1 (0.52) | EPHX2XDH | |
| SCHEMBL19445672 | 0.79 | KMT2A (0.63) | KMT2AMEN1KDM4ERXFP1RAB9A | |
| SCHEMBL28125494 | 0.77 | XDH (0.61) | KMT2AMEN1KDM4ERXFP1RAB9A | |
| SCHEMBL14640451 | 0.77 | DRD2 (0.67) | KMT2AMEN1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |