Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082528 | 0.81 | MAPK1 (0.78) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14640450 | 0.79 | RAB9A (0.52) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL14640454 | 0.79 | HDAC1 (0.78) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14252956 | 0.78 | SMN1; SMN2 (0.77) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1968315 | 0.78 | MAPK1 (0.74) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL14640424 | 0.78 | HTT (0.63) | GAAMAPTKDM1AHDAC1POLB | |
| SCHEMBL14640423 | 0.76 | RAB9A (0.55) | MAPK1NPC1RAB9AKDM1AHDAC1 | |
| SCHEMBL29008967 | 0.76 | GAA (0.70) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1971770 | 0.76 | MAPK1 (1.00) | MAPK1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL29356619 | 0.75 | ALDH1A1 (0.77) | MAPK1ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |