Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640819 | 0.83 | GPR119 (0.54) | GPR119NAAAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL14640818 | 0.83 | GPR119 (0.46) | GPR119PLAT | |
| SCHEMBL14640645 | 0.82 | NAAA (0.44) | GPR119NAAAMAPTTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3935192 | 0.82 | ALDH1A1 (0.49) | MAPTMMP2MMP9MMP14THRB | |
| SCHEMBL4528547 | 0.81 | GPR119 (0.58) | GPR119NAAAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL13598319 | 0.81 | GPR119 (0.49) | GPR119NAAAMAPT | |
| SCHEMBL4414400 | 0.80 | USP7 (0.41) | CA1CA2CA9PLAT | |
| SCHEMBL27742207 | 0.79 | GPR119 (0.57) | GPR119NAAATSHR | |
| SCHEMBL4424816 | 0.78 | GPR119 (0.58) | GPR119SMN1; SMN2 | |
| SCHEMBL4420442 | 0.78 | GPR119 (0.77) | GPR119HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |