SCHEMBL14640649

SCHEMBL14640649

CSc1ccc(-c2nc(COC3CCNCC3)no2)cc1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 1/20 0.43
NMT1 P30419 13/20 0.40
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4414400 0.82 USP7 (0.41) USP7NMT1MAOB
SCHEMBL14640816 0.82 USP7 (0.41) USP7NMT1MAOB
SCHEMBL14640897 0.80 SPHK1 (0.46) USP7
SCHEMBL13186626 0.78 NMT1 (0.40) USP7NMT1MAOB
SCHEMBL13598193 0.77 GPR119 (0.54)
SCHEMBL27742206 0.76 SPHK1 (0.41) USP7NMT1MAOB
SCHEMBL14640895 0.76 SPHK1 (0.48)
SCHEMBL14640893 0.76 SPHK1 (0.49) USP7
SCHEMBL14640892 0.75 USP7 (0.38) USP7MAOB
SCHEMBL4415589 0.75 GPR119 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007003960-A1 GPCR AGONISTS PROSIDION LIMITED (GB) 2007-01-11 WO disclosed