Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412654 | 0.86 | GPR119 (0.40) | SPHK1PTGS2HDAC4SPHK2KCNH2 | |
| SCHEMBL13598289 | 0.83 | GPR119 (0.55) | — | |
| SCHEMBL14640895 | 0.82 | SPHK1 (0.48) | SPHK1HDAC4SPHK2HDAC6SMPD1 | |
| SCHEMBL14640897 | 0.82 | SPHK1 (0.46) | USP7SPHK1HDAC4SPHK2HDAC6 | |
| SCHEMBL27742206 | 0.78 | SPHK1 (0.41) | USP7SPHK1SPHK2SMPD1MAOB | |
| SCHEMBL14640893 | 0.78 | SPHK1 (0.49) | USP7SPHK1PTGS2HDAC4SPHK2 | |
| SCHEMBL14640693 | 0.77 | SPHK1 (0.45) | USP7SPHK1PTGS2HDAC4SPHK2 | |
| SCHEMBL4414400 | 0.76 | USP7 (0.41) | USP7MAOB | |
| SCHEMBL4422301 | 0.76 | GPR119 (0.55) | HDAC4 | |
| SCHEMBL14640649 | 0.75 | USP7 (0.43) | USP7MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |