Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640895 | 0.92 | SPHK1 (0.48) | SPHK1SPHK2HDAC6HDAC4SMPD1 | |
| SCHEMBL4416417 | 0.82 | GPR119 (0.55) | SPHK2HDAC6HDAC4 | |
| SCHEMBL14640892 | 0.82 | USP7 (0.38) | SPHK1SPHK2HDAC6HDAC4SMPD1 | |
| SCHEMBL27742206 | 0.80 | SPHK1 (0.41) | SPHK1SPHK2SMPD1USP7 | |
| SCHEMBL14640893 | 0.80 | SPHK1 (0.49) | SPHK1SPHK2HDAC6HDAC4MCHR1 | |
| SCHEMBL14640649 | 0.80 | USP7 (0.43) | USP7 | |
| SCHEMBL14640693 | 0.79 | SPHK1 (0.45) | SPHK1SPHK2HDAC4USP7 | |
| SCHEMBL4414400 | 0.78 | USP7 (0.41) | USP7 | |
| SCHEMBL14640816 | 0.76 | USP7 (0.41) | USP7 | |
| SCHEMBL4424803 | 0.76 | SPHK1 (0.46) | SPHK1SPHK2HDAC6HDAC4SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |