SCHEMBL14640698

SCHEMBL14640698

CC(C)N(C(C)C)P(OCCC#N)OCc1cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAOB P27338 4/20 0.37
GUSB P08236 2/20 0.36
SGMS2 Q8NHU3 1/20 0.36
BCHE P06276 2/20 0.35
RRM1 P23921 1/20 0.35
KCNH2 Q12809 1/20 0.35
MCHR1 Q99705 1/20 0.35
AR P10275 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4881259 0.89 MAOB (0.36) MAOBGUSB
SCHEMBL14601806 0.87 MAOB (0.35) MEN1KMT2AMAOBBCHERRM1
SCHEMBL12904940 0.80 MAOB (0.36) MEN1KMT2AMAOB
Acetonitrile SCHEMBL27856444 0.78 MAOB (0.37) KMT2AMAOB
SCHEMBL13073522 0.77
SCHEMBL22762194 0.76
SCHEMBL80897 0.76 TSHR (0.41) MEN1KMT2AKCNH2
SCHEMBL2229214 0.76 MRGPRX4 (0.34) MEN1KMT2A
SCHEMBL27474 0.76 ALDH1A1 (0.34) MAOB
SCHEMBL14601794 0.76 CTSS (0.39) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070015927-A1 New phosphoramidite compounds POSTECH FOUNDATION (KR) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015927-A1 New phosphoramidite compounds TYMP, POLRMT, POLI MEN1 1608/4885KMT2A 3029/4885MAOB 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.