SCHEMBL1464077

SCHEMBL1464077

C=COC(=O)C12CC3CC(C1)CC(C(=O)OC=C)(C3)C2

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.35
MAPT P10636 2/20 0.35
THRB P10828 1/20 0.35
GAA P10253 1/20 0.35
XBP1 P17861 1/20 0.35
HSD11B1 P28845 1/20 0.33
PKM P14618 1/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28413574 0.90 ALDH1A1 (0.49) NPSR1SMN1; SMN2LMNAALDH1A1L3MBTL1
SCHEMBL19506897 0.88 NPSR1 (0.33) NPSR1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL5374123 0.88 MAPT (0.44) NPSR1LMNAMEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL15398368 0.81 PRKCA (0.44) NPSR1MEN1KMT2AALDH1A1MAPT
Acetic Acid SCHEMBL27569637 0.81 SCN1A (0.41) NPSR1MEN1KMT2AALDH1A1MAPT
SCHEMBL19506905 0.77
SCHEMBL8028307 0.77 ALDH1A1 (0.33) NPSR1KMT2AALDH1A1
SCHEMBL6559153 0.77 NPSR1 (0.53) NPSR1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL7797328 0.75 MEN1 (0.47) NPSR1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL163027 0.74 NPSR1 (0.53) NPSR1SMN1; SMN2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10042272-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-08-07 US disclosed
US-10042272-B2 Electrophotographic photosensitive member, method for producing the same, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-08-07 US disclosed
EP-2298841-B1 Ink composition, and inkjet recording method FUJIFILM CORP (JP) 2017-10-25 EP disclosed
US-20170299971-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
US-20170299971-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
US-8361563-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-01-29 US disclosed
EP-2230284-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2011-08-03 EP disclosed
US-20110071239-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2011-03-24 US disclosed
EP-2298841-A1 Ink composition, and inkjet recording method FUJIFILM Corporation (JP) 2011-03-23 EP disclosed
US-20100239779-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
EP-2230284-A1 Ink composition and inkjet recording method Fujifilm Corporation (JP) 2010-09-22 EP disclosed