Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3935192 | 0.80 | ALDH1A1 (0.49) | HDAC4CA12CA1CA2CA9 | |
| SCHEMBL12659969 | 0.79 | IKBKB (0.46) | PTGS2PTGS1GPR183GPR119IKBKB | |
| SCHEMBL4418694 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL12659968 | 0.77 | TDP1 (0.58) | PTGS2PTGS1GPR183GPR119IKBKB | |
| SCHEMBL14894431 | 0.76 | CA12 (0.62) | CA12CA1CA2CA9FAAH | |
| Hydrochloric Acid SCHEMBL384404 | 0.76 | TDP1 (0.61) | PTGS2PTGS1GPR183GPR119IKBKB | |
| SCHEMBL14640643 | 0.76 | GPR119 (0.48) | GPR119HDAC4CA12CA1CA2 | |
| SCHEMBL5564172 | 0.75 | TDP1 (0.63) | PTGS2PTGS1IKBKBCHUKKDM1A | |
| SCHEMBL3982941 | 0.74 | KDM1A (0.48) | PTGS2PTGS1IKBKBCHUKKDM1A | |
| Hydrochloric Acid SCHEMBL387125 | 0.74 | KDM1A (0.47) | PTGS2PTGS1IKBKBCHUKKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |