Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 20/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640946 | 0.84 | PYGL (0.54) | PYGLABCB11 | |
| SCHEMBL14404226 | 0.84 | PYGL (0.65) | PYGLABCB11 | |
| SCHEMBL5643306 | 0.77 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL5643375 | 0.77 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL14641138 | 0.74 | PYGL (0.57) | PYGL | |
| SCHEMBL5629137 | 0.71 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL5629430 | 0.71 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL14380797 | 0.71 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL5631028 | 0.71 | PYGL (1.00) | PYGLABCB11 | |
| SCHEMBL5633029 | 0.71 | PYGL (1.00) | PYGLABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169927-B2 | Indole-amide derivatives and their use as glycogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2007-01-30 | — | — | US | disclosed |