Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.57 |
| ▸ | PYGM | P11217 | 8/20 | 0.57 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891413 | 0.84 | PYGL (0.52) | PYGLPYGMF11GAAMAPT | |
| SCHEMBL13891430 | 0.79 | PYGL (0.50) | PYGLPYGMF11GAAMAPT | |
| SCHEMBL21740214 | 0.77 | PYGL (0.47) | PYGLPYGMF11GAAMAPT | |
| SCHEMBL14640946 | 0.75 | PYGL (0.54) | PYGLPYGM | |
| SCHEMBL13891446 | 0.74 | PYGL (0.39) | PYGLPYGMF11GAARIPK1 | |
| SCHEMBL14640945 | 0.74 | PYGL (0.62) | PYGL | |
| SCHEMBL764562 | 0.73 | RAB9A (0.47) | MAPT | |
| SCHEMBL25329367 | 0.73 | PYGL (0.64) | PYGLPYGMGAAMAPTRIPK1 | |
| SCHEMBL29900499 | 0.73 | PYGL (0.64) | PYGLPYGMGAAMAPTRIPK1 | |
| SCHEMBL15541576 | 0.73 | PYGL (0.64) | PYGLPYGMGAAMAPTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169927-B2 | Indole-amide derivatives and their use as glycogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2007-01-30 | — | — | US | disclosed |