Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 20/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640945 | 0.84 | PYGL (0.62) | PYGLABCB11 | |
| SCHEMBL4801804 | 0.76 | PYGL (0.78) | PYGLABCB11PYGM | |
| SCHEMBL5642230 | 0.76 | PYGL (0.78) | PYGLABCB11PYGM | |
| SCHEMBL4804137 | 0.76 | PYGL (0.78) | PYGLABCB11PYGM | |
| SCHEMBL14641138 | 0.75 | PYGL (0.57) | PYGLPYGM | |
| SCHEMBL13891451 | 0.72 | PYGL (0.54) | PYGL | |
| SCHEMBL14404397 | 0.70 | PYGL (0.63) | PYGL | |
| SCHEMBL5629243 | 0.70 | PYGL (1.00) | PYGL | |
| SCHEMBL13891478 | 0.70 | PYGL (0.37) | PYGL | |
| SCHEMBL13878951 | 0.69 | PYGL (0.69) | PYGLABCB11PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169927-B2 | Indole-amide derivatives and their use as glycogen phosphorylase inhibitors | ASTRAZENECA AB (SE) | 2007-01-30 | — | — | US | disclosed |