Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464122 | 1.00 | FDPS (0.44) | FDPSGGPS1HSD17B10GMNNTP53 | |
| SCHEMBL17183982 | 0.91 | HSD17B10 (0.38) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL7779023 | 0.88 | FDPS (0.44) | FDPSGGPS1HSD17B10GMNNTP53 | |
| SCHEMBL11550381 | 0.82 | GMNN (0.48) | FDPSGGPS1HSD17B10GMNNTP53 | |
| SCHEMBL7774055 | 0.78 | HSD17B10 (0.38) | HSD17B10GMNNTP53POLBMAPT | |
| SCHEMBL30409240 | 0.77 | CES2 (0.44) | GGPS1HSD17B10CES2PPARGPPARD | |
| SCHEMBL11351778 | 0.76 | FDPS (0.48) | FDPSGGPS1HSD17B10CES2PPARG | |
| SCHEMBL380072 | 0.76 | FDPS (0.48) | FDPSGGPS1HSD17B10CES2PPARG | |
| SCHEMBL1990820 | 0.76 | FDPS (0.48) | FDPSGGPS1HSD17B10CES2PPARG | |
| SCHEMBL11220213 | 0.76 | FDPS (0.48) | FDPSGGPS1HSD17B10CES2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362014-B2 | ABT-263 crystalline forms | ABBVIE INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110071151-A1 | ABT-263 CRYSTALLINE FORMS | ABBOTT LABORATORIES (US) | 2011-03-24 | — | — | US | disclosed |
| US-20100323020-A1 | STABLE NANOPARTICULATE DRUG SUSPENSION | ABBOTT LABORATORIES (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323020-A1 | STABLE NANOPARTICULATE DRUG SUSPENSION | BCL2L10, TMBIM6, BCOR | FDPS 4484/4885GGPS1 4385/4885HSD17B10 2721/4885 |
| US-20110071151-A1 | ABT-263 CRYSTALLINE FORMS | BCL3, BCL2, BCL2L13 | FDPS 4433/4885GGPS1 4504/4885HSD17B10 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.